| W-L | URPI | Rank | SOS | Rank | ||
|---|---|---|---|---|---|---|
| Date | Rank | Opponent | Result | ||
|---|---|---|---|---|---|
| 11/9 | 7 | vs. Kentucky | W | 79-71 | Champions Classic |
| 11/12 | 246 | Army | W | 82-56 | Duke Veterans Day Weekend Showcase |
| 11/13 | 210 | Campbell | W | 67-56 | Duke Veterans Day Weekend Showcase |
| 11/16 | 180 | Gardner-Webb | W | 92-52 | |
| 11/19 | 307 | Lafayette | W | 88-55 | |
| 11/22 | 227 | The Citadel | W | 107-81 | |
| 11/26 | 1 | vs. Gonzaga | W | 84-81 | Continental Tire Challenge |
| 11/30 | 58 | @ Ohio St. | L | 66-71 | ACC/Big Ten Challenge |
| 12/14 | 288 | South Carolina St. | W | 103-62 | |
| 12/16 | 118 | Appalachian St. | W | 92-67 | |
| 12/18 | 274 | Elon | W | 87-56 | |
| 12/22 | 56 | Virginia Tech | W | 76-65 | |
| 1/4 | 255 | Georgia Tech | W | 69-57 | |
| 1/8 | 53 | Miami (FL) | L | 74-76 | |
| 1/12 | 66 | @ Wake Forest | W | 76-64 | |
| 1/15 | 226 | NC State | W | 88-73 | |
| 1/18 | 122 | @ Florida St. | L | 78-79 | |
| 1/22 | 139 | Syracuse | W | 79-59 | |
| 1/25 | 143 | Clemson | W | 71-69 | |
| 1/29 | 203 | @ Louisville | W | 74-65 | |
| 1/31 | 60 | @ Notre Dame | W | 57-43 | |
| 2/5 | 40 | @ North Carolina | W | 87-67 | |
| 2/7 | 101 | Virginia | L | 68-69 | |
| 2/10 | 143 | @ Clemson | W | 82-64 | |
| 2/12 | 242 | @ Boston College | W | 72-61 | |
| 2/15 | 66 | Wake Forest | W | 76-74 | |
| 2/19 | 122 | Florida St. | W | 88-70 | |
| 2/23 | 101 | @ Virginia | W | 65-61 | |
| 2/26 | 139 | @ Syracuse | W | 97-72 | |
| 3/1 | 238 | @ Pittsburgh | W | 86-56 | |
| 3/5 | 40 | North Carolina | L | 81-94 | |
| 3/10 | 139 | vs. Syracuse | W | 88-79 | ACC Tournament |
| 3/11 | 53 | vs. Miami (FL) | W | 80-76 | ACC Tournament |
| 3/12 | 56 | vs. Virginia Tech | L | 67-82 | ACC Tournament |